The term Code Zero was coined in the first Joe Ledger book, Patient Zero, to indicate a threat composed of the Seif-al-Din virus, which if released would inflict a zombie plague upon the world. This book is pretty much a sequel to that first book with a smattering of threats from the other books thrown in for good measure. Over the course of the first five books of the series Joe Ledger and the DMS have turned aside one threat after another (designer plagues, pathogens, engineered viruses, etc) and they have been locking away samples of these threats in their most secure facility. Very few people even know these things exist and all of these secrets are closely guarded for good reason. However, this time around the threat comes from within the DMS itself and that makes it hard for Joe Ledger and Echo team to get the job done as they are unaware they have been betrayed...
Code Zero - Joe Ledger #6 is a trip down memory lane